R.I.P. Peggy Jones, better known as, Lady Bo.

Groundbreaking guitarist known for her work alongside Bo Diddley, performing on such classics as Hey, Bo Diddley and Road Runner, Lady Bo also contributed one of the best instrumentals in the Diddley repertoire, Aztec, to 1961’s, Bo Diddley Is A Lover. In addition to Diddley duty, Lady Bo performed in The Jewels (and both Family Jewels and Fabulous Jewels), and with fellow Diddley alum Bob Baskerville, in Bob & Peggy, among other acts (check link below for full discog).

http://members.tripod.com/~Originator_2/ladybo.html

While there are several vintage Bo performance clips online with a female guitarist, often credited as Lady Bo, to the best of my knowledge, those clips actually feature her successor, The Duchess.